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Other, less common melatonin side effects might include short-lasting feelings of depression, mild tremor, mild anxiety, abdominal cramps, irritability, reduced. You might feel particularly uncomfortable in hotter or colder temperatures, which could contribute to you developing depression (or any existing depression. This overproduction of melatonin leads to seasonal affective disorder (SAD), a mood disorder that affects an estimated 10 to 20 percent of the population.

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Mood changes have been reported, both highs and lows, and even psychotic symptoms such as hallucinations and paranoia. Persons with major depression or. Melatonin, a sleep-related hormone, also has been linked to SAD. The body naturally makes more melatonin when it's dark. So when the days are shorter and darker. Excess melatonin does not cause seasonal affective disorder, but it can cause atypical depressive symptoms, such as increased tiredness or sleepiness.

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Melatonin has been reported to reduce body temperature which could keep the drug from being useful during cold stress. Central nervous system effects . What causes SAD? · production of melatonin – melatonin is a hormone that makes you feel sleepy; in people with SAD, the body may produce it in higher than normal. Excess melatonin does not cause seasonal affective disorder, but it can cause atypical depressive symptoms, such as increased tiredness or sleepiness.